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A kinesin-13 mutant catalytically depolymerizes microtubules in ADP
The kinesin-13 motor protein family members drive the removal of tubulin from microtubules (MTs) to promote MT turnover. A point mutation of the kinesin-13 family member mitotic centromere-associated kinesin/Kif2C (E491A) isolates the tubulin-removal conformation of the motor, and appears distinct f...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2582896/ https://ncbi.nlm.nih.gov/pubmed/19001124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805145 |
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