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The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization

Unlike other kinesins, members of the kinesin-13 subfamily do not move directionally along microtubules but, instead, depolymerize them. To understand how kinesins with structurally similar motor domains can have such dissimilar functions, we elucidated the ATP turnover cycle of the kinesin-13, MCAK...

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Detalles Bibliográficos
Main Authors: Friel, Claire T, Howard, Jonathon
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209780/
https://ncbi.nlm.nih.gov/pubmed/21873978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.290
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