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G(1) and G(2) cell-cycle arrest following microtubule depolymerization in human breast cancer cells

Microtubule-depolymerizing agents are widely used to synchronize cells, screen for mitotic checkpoint defects, and treat cancer. The present study evaluated the effects of these agents on normal and malignant human breast cell lines. After treatment with 1 μM nocodazole, seven of ten breast cancer l...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Blajeski, April L., Phan, Vy A., Kottke, Timothy J., Kaufmann, Scott H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2002
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC151025/
https://ncbi.nlm.nih.gov/pubmed/12093892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI13275
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