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Mitochondrial apoptosis and BH3 mimetics

The BCL2-selective BH3 mimetic venetoclax was recently approved for the treatment of relapsed, chromosome 17p-deleted chronic lymphocytic leukemia (CLL) and is undergoing extensive testing, alone and in combination, in lymphomas, acute leukemias, and solid tumors. Here we summarize recent advances i...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: Dai, Haiming, Meng, X. Wei, Kaufmann, Scott H.
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133681/
https://ncbi.nlm.nih.gov/pubmed/27990281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.9629.1
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