A carregar...
DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis
The concept of using BH3 mimetics as anticancer agents has been substantiated by the efficacy of selective drugs, such as Navitoclax and Venetoclax, in treating BCL-2-dependent haematological malignancies. However, most solid tumours depend on MCL-1 for survival, which is highly amplified in multipl...
Na minha lista:
| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5386385/ https://ncbi.nlm.nih.gov/pubmed/28079887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.485 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|