DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis

Maintenance of mitochondrial integrity is critical for normal cellular homoeostasis. Most cells respond to stress stimuli and undergo apoptosis by perturbing mitochondrial structure and function to release proteins, such as cytochrome c, which are essential for the execution of the intrinsic apoptot...

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Detalles Bibliográficos
Publicado en:Cell Death Discov
Main Authors: Milani, Mateus, Beckett, Alison J., Al-Zebeeby, Aoula, Luo, Xu, Prior, Ian A., Cohen, Gerald M., Varadarajan, Shankar
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637195/
https://ncbi.nlm.nih.gov/pubmed/31341643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-019-0199-x
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