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DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis

Maintenance of mitochondrial integrity is critical for normal cellular homoeostasis. Most cells respond to stress stimuli and undergo apoptosis by perturbing mitochondrial structure and function to release proteins, such as cytochrome c, which are essential for the execution of the intrinsic apoptot...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Milani, Mateus, Beckett, Alison J., Al-Zebeeby, Aoula, Luo, Xu, Prior, Ian A., Cohen, Gerald M., Varadarajan, Shankar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637195/
https://ncbi.nlm.nih.gov/pubmed/31341643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-019-0199-x
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