Co-selected mutations in VCP: a novel mechanism of resistance to VCP inhibitors

by Bastola, Prabhakar, Chien, Jeremy
Published in Cell Death Dis (2018)

Ovarian cancer prevention, screening and early detection: Report from the 11(th) Biennial Ovarian Cancer Research Symposium

by Chien, Jeremy, Poole, Elizabeth M.
Published in Int J Gynecol Cancer (2017)

IDENTIFICATION OF TUBULINS AS SUBSTRATES OF SERINE PROTEASE HTRA1 BY MIXTURE-BASED ORIENTED PEPTIDE LIBRARY SCREENING

by Chien, Jeremy, He, Xiaoping, Shridhar, Viji
Published 2009

Regulation of chemo-sensitivity in ovarian cancer via a stroma dependent glutathione pathway

by Oien, Derek B., Chien, Jeremy, Cheng, Nikki
Published in Transl Cancer Res (2016)

High Temperature Requirement A3 (HtrA3) Promotes Etoposide- and Cisplatin-induced Cytotoxicity in Lung Cancer Cell Lines

by Beleford, Daniah, Rattan, Ramandeep, Chien, Jeremy, Shridhar, Viji
Published 2010

Platinum-Sensitive Recurrence in Ovarian Cancer: The Role of Tumor Microenvironment

by Chien, Jeremy, Kuang, Rui, Landen, Charles, Shridhar, Viji
Published 2013

HtrA Serine Proteases as Potential Therapeutic Targets in Cancer

by Chien, Jeremy, Campioni, Mara, Shridhar, Viji, Baldi, Alfonso
Published 2009

Network-based machine learning and graph theory algorithms for precision oncology

by Zhang, Wei, Chien, Jeremy, Yong, Jeongsik, Kuang, Rui
Published in NPJ Precis Oncol (2017)

VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase‐mediated cell death and synergistically kill ovarian cancer cells in combination with S...

by Bastola, Prabhakar, Neums, Lisa, Schoenen, Frank J., Chien, Jeremy
Published in Mol Oncol (2016)

Cisplatin and Pemetrexed Activate AXL and AXL Inhibitor BGB324 Enhances Mesothelioma Cell Death from Chemotherapy

by Oien, Derek B., Garay, Tamás, Eckstein, Sarah, Chien, Jeremy
Published in Front Pharmacol (2018)

Genome-scale CRISPR knockout screen identifies TIGAR as a modifier of PARP inhibitor sensitivity

by Fang, Pingping, De Souza, Cristabelle, Minn, Kay, Chien, Jeremy
Published in Commun Biol (2019)

Role of heparan sulfatases in ovarian and breast cancer

by Khurana, Ashwani, Beleford, Daniah, He, Xiaoping, Chien, Jeremy, Shridhar, Viji
Published 2013

HtrA1 sensitizes ovarian cancer cells to cisplatin-induced cytotoxicity by targeting XIAP for degradation

by He, Xiaoping, Khurana, Ashwani, Maguire, Jacie L, Chien, Jeremy, Shridhar, Viji
Published 2011

Heterozygous mutations in valosin-containing protein (VCP) and resistance to VCP inhibitors

by Bastola, Prabhakar, Bilkis, Rabeya, De Souza, Cristabelle, Minn, Kay, Chien, Jeremy
Published in Sci Rep (2019)

Network-based Survival Analysis Reveals Subnetwork Signatures for Predicting Outcomes of Ovarian Cancer Treatment

by Zhang, Wei, Ota, Takayo, Shridhar, Viji, Chien, Jeremy, Wu, Baolin, Kuang, Rui
Published 2013

Down-regulation of HtrA1 promotes resistance to anoikis and peritoneal dissemination of ovarian cancer cells

by He, Xiaoping, Ota, Takayo, Liu, Peng, Su, Changqing, Chien, Jeremy, Shridhar, Viji
Published in Cancer Res (2010)

Changes in O-Linked N-Acetylglucosamine (O-GlcNAc) Homeostasis Activate the p53 Pathway in Ovarian Cancer Cells

by de Queiroz, Rafaela Muniz, Madan, Rashna, Chien, Jeremy, Dias, Wagner Barbosa, Slawson, Chad
Published in J Biol Chem (2016)

digit—a tool for detection and identification of genomic interchromosomal translocations

by Meier, Richard, Graw, Stefan, Beyerlein, Peter, Koestler, Devin, Molina, Julian R., Chien, Jeremy
Published in Nucleic Acids Res (2017)

VaDiR: an integrated approach to Variant Detection in RNA

by Neums, Lisa, Suenaga, Seiji, Beyerlein, Peter, Anders, Sara, Koestler, Devin, Mariani, Andrea, Chien, Jeremy
Published in Gigascience (2017)

Targeting of mutant p53-induced FoxM1 with thiostrepton induces cytotoxicity and enhances carboplatin sensitivity in cancer cells

by Zhang, Xuan, Cheng, Lihua, Minn, Kay, Madan, Rashna, Godwin, Andrew K., Shridhar, Viji, Chien, Jeremy
Published in Oncotarget (2014)