Epigenetic silencing of serine protease HTRA1 drives polyploidy

BACKGROUND: Increased numbers and improperly positioned centrosomes, aneuploidy or polyploidy, and chromosomal instability are frequently observed characteristics of cancer cells. While some aspects of these events and the checkpoint mechanisms are well studied, not all players have yet been identif...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Schmidt, Nina, Irle, Inga, Ripkens, Kamilla, Lux, Vanda, Nelles, Jasmin, Johannes, Christian, Parry, Lee, Greenow, Kirsty, Amir, Sarah, Campioni, Mara, Baldi, Alfonso, Oka, Chio, Kawaichi, Masashi, Clarke, Alan R., Ehrmann, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936022/
https://ncbi.nlm.nih.gov/pubmed/27388476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2425-8
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