Tau Biology and Tau-Directed Therapies for Alzheimer’s Disease

Por Bakota, Lidia, Brandt, Roland
Publicado no Drugs (2016)

Divergent Pathways Mediate Spine Alterations and Cell Death Induced by Amyloid-β, Wild-Type Tau, and R406W Tau

Por Tackenberg, Christian, Brandt, Roland
Publicado no J Neurosci (2009)

Signaling pathways and posttranslational modifications of tau in Alzheimer's disease: the humanization of yeast cells

Por Heinisch, Jürgen J., Brandt, Roland
Publicado no Microb Cell (2016)

Tau-Mediated Cytotoxicity in a Pseudohyperphosphorylation Model of Alzheimer's Disease

Por Fath, Thomas, Eidenmüller, Jochen, Brandt, Roland
Publicado no J Neurosci (2002)

Much More Than a Cytoskeletal Protein: Physiological and Pathological Functions of the Non-microtubule Binding Region of Tau

Por Brandt, Roland, Trushina, Nataliya I., Bakota, Lidia
Publicado no Front Neurol (2020)

Real‐time three‐dimensional echocardiographic diagnosis of postmyocardial infarction ventricular septal defect and guidance of transcatheter closure

Por Brandt, Roland R, Elsaesser, Albrecht, Hamm, Christian W
Publicado em 2007

Tau Binds to the Distal Axon Early in Development of Polarity in a Microtubule- and Microfilament-Dependent Manner

Por Kempf, Martina, Clement, Albrecht, Faissner, Andreas, Lee, Gloria, Brandt, Roland
Publicado no J Neurosci (1996)

Tau Aggregation and Progressive Neuronal Degeneration in the Absence of Changes in Spine Density and Morphology after Targeted Expression of Alzheimer's Disease-Relevant Tau Constr...

Por Shahani, Neelam, Subramaniam, Srinivasa, Wolf, Tobias, Tackenberg, Christian, Brandt, Roland
Publicado no J Neurosci (2006)

The Evolution of Tau Phosphorylation and Interactions

Por Trushina, Nataliya I., Bakota, Lidia, Mulkidjanian, Armen Y., Brandt, Roland
Publicado no Front Aging Neurosci (2019)

A Refined Reaction-Diffusion Model of Tau-Microtubule Dynamics and Its Application in FDAP Analysis

Por Igaev, Maxim, Janning, Dennis, Sündermann, Frederik, Niewidok, Benedikt, Brandt, Roland, Junge, Wolfgang
Publicado no Biophys J (2014)

Presence of a carboxy-terminal pseudorepeat and disease-like pseudohyperphosphorylation critically influence tau’s interaction with microtubules in axon-like processes

Por Niewidok, Benedikt, Igaev, Maxim, Sündermann, Frederik, Janning, Dennis, Bakota, Lidia, Brandt, Roland
Publicado no Mol Biol Cell (2016)

Evaluation Of Atrial Fibrillation Burden Before Catheter Ablation Predicts Outcome After Pulmonary Vein Isolation

Por Berkowitsch, Alexander, Neumann, Thomas, Kuniss, Malte, Brandt, Roland, Zaltsberg, Sergej, Pitschner, Heinz F
Publicado em 2009

Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative process...

Por Golovyashkina, Nataliya, Penazzi, Lorène, Ballatore, Carlo, Smith, Amos B., Bakota, Lidia, Brandt, Roland
Publicado no Mol Neurodegener (2015)

Insulin-Like Growth Factor 1 Inhibits Extracellular Signal-Regulated Kinase to Promote Neuronal Survival via the Phosphatidylinositol 3-Kinase/Protein Kinase A/c-Raf Pathway

Por Subramaniam, Srinivasa, Shahani, Neelam, Strelau, Jens, Laliberté, Christine, Brandt, Roland, Kaplan, David, Unsicker, Klaus
Publicado no J Neurosci (2005)

Process Outgrowth of Oligodendrocytes Is Promoted by Interaction of Fyn Kinase with the Cytoskeletal Protein Tau

Por Klein, Corinna, Krämer, Eva-Maria, Cardine, Anne-Marie, Schraven, Burkhardt, Brandt, Roland, Trotter, Jacqueline
Publicado no J Neurosci (2002)

Regulation between O-GlcNAcylation and phosphorylation of neurofilament-M and their dysregulation in Alzheimer disease

Por Deng, Yanqiu, Li, Bin, Liu, Fei, Iqbal, Khalid, Grundke-Iqbal, Inge, Brandt, Roland, Gong, Cheng-Xin
Publicado em 2007

RNA Protein Granules Modulate tau Isoform Expression and Induce Neuronal Sprouting

Por Moschner, Katharina, Sündermann, Frederik, Meyer, Heiko, da Graca, Abel Pereira, Appel, Neele, Paululat, Achim, Bakota, Lidia, Brandt, Roland
Publicado em 2014

Pseudohyperphosphorylation of tau is sufficient to induce aberrant sprouting and activation of ERK1/2 in transgenic mice

Por Monyer Hannah, von Engelhardt Jacob, Götz Jürgen, Schultz Christian, Fath Thomas, Kosfeld Anne, Selle Karolin, Hundelt Monika, Brandt Roland
Publicado em 2007-03-01

The frontotemporal dementia mutation R406W blocks tau’s interaction with the membrane in an annexin A2–dependent manner

Por Gauthier-Kemper, Anne, Weissmann, Carina, Golovyashkina, Nataliya, Sebö-Lemke, Zsofia, Drewes, Gerard, Gerke, Volker, Heinisch, Jürgen J., Brandt, Roland
Publicado em 2011

Early Effects of Aβ Oligomers on Dendritic Spine Dynamics and Arborization in Hippocampal Neurons

Por Ortiz-Sanz, Carolina, Gaminde-Blasco, Adhara, Valero, Jorge, Bakota, Lidia, Brandt, Roland, Zugaza, José L., Matute, Carlos, Alberdi, Elena
Publicado no Front Synaptic Neurosci (2020)