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Tau-Mediated Cytotoxicity in a Pseudohyperphosphorylation Model of Alzheimer's Disease

Aggregation and increased phosphorylation of tau at selected sites (“hyperphosphorylation”) are histopathological hallmarks of Alzheimer's disease (AD). However, it is not known whether the tau pathology has a primary role during neuronal degeneration. To determine the role of tau hyperphosphor...

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Vydáno v:J Neurosci
Hlavní autoři: Fath, Thomas, Eidenmüller, Jochen, Brandt, Roland
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757822/
https://ncbi.nlm.nih.gov/pubmed/12427828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-22-09733.2002
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