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Modeling of Tau-Mediated Synaptic and Neuronal Degeneration in Alzheimer's Disease

Patients suffering from Alzheimer's disease (AD) are typified and diagnosed postmortem by the combined accumulations of extracellular amyloid plaques and of intracellular tauopathy, consisting of neuropil treads and neurofibrillary tangles in the somata. Both hallmarks are inseparable and remai...

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Autori principali: Jaworski, Tomasz, Kügler, Sebastian, Van Leuven, Fred
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE-Hindawi Access to Research 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938448/
https://ncbi.nlm.nih.gov/pubmed/20862366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/573138
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