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Modeling of Tau-Mediated Synaptic and Neuronal Degeneration in Alzheimer's Disease

Patients suffering from Alzheimer's disease (AD) are typified and diagnosed postmortem by the combined accumulations of extracellular amyloid plaques and of intracellular tauopathy, consisting of neuropil treads and neurofibrillary tangles in the somata. Both hallmarks are inseparable and remai...

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Detalhes bibliográficos
Main Authors: Jaworski, Tomasz, Kügler, Sebastian, Van Leuven, Fred
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938448/
https://ncbi.nlm.nih.gov/pubmed/20862366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/573138
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