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Modeling of Tau-Mediated Synaptic and Neuronal Degeneration in Alzheimer's Disease

Patients suffering from Alzheimer's disease (AD) are typified and diagnosed postmortem by the combined accumulations of extracellular amyloid plaques and of intracellular tauopathy, consisting of neuropil treads and neurofibrillary tangles in the somata. Both hallmarks are inseparable and remai...

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Detalles Bibliográficos
Main Authors: Jaworski, Tomasz, Kügler, Sebastian, Van Leuven, Fred
Formato: Artigo
Idioma:Inglês
Publicado: SAGE-Hindawi Access to Research 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938448/
https://ncbi.nlm.nih.gov/pubmed/20862366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/573138
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