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Modeling of Tau-Mediated Synaptic and Neuronal Degeneration in Alzheimer's Disease

Patients suffering from Alzheimer's disease (AD) are typified and diagnosed postmortem by the combined accumulations of extracellular amyloid plaques and of intracellular tauopathy, consisting of neuropil treads and neurofibrillary tangles in the somata. Both hallmarks are inseparable and remai...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jaworski, Tomasz, Kügler, Sebastian, Van Leuven, Fred
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE-Hindawi Access to Research 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938448/
https://ncbi.nlm.nih.gov/pubmed/20862366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/573138
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