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Tau Biology and Tau-Directed Therapies for Alzheimer’s Disease

Alzheimer’s disease (AD) is characterised by a progressive loss of cognitive functions. Histopathologically, AD is defined by the presence of extracellular amyloid plaques containing Aβ and intracellular neurofibrillary tangles composed of hyperphosphorylated tau proteins. According to the now well-...

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Detalhes bibliográficos
Publicado no:Drugs
Main Authors: Bakota, Lidia, Brandt, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757605/
https://ncbi.nlm.nih.gov/pubmed/26729186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40265-015-0529-0
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