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Tau-targeting therapies for Alzheimer disease
Alzheimer disease (AD) is the most common form of dementia. Pathologically, AD is characterized by amyloid plaques and neurofibrillary tangles in the brain, with associated loss of synapses and neurons, resulting in cognitive deficits and eventually dementia. Amyloid-β (Aβ) peptide and tau protein a...
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| Publicado no: | Nat Rev Neurol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6463489/ https://ncbi.nlm.nih.gov/pubmed/29895964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41582-018-0013-z |
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