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Tau as a Therapeutic Target for Alzheimer’s Disease

Neurofibrillary tangles (NFTs) are one of the pathological hallmarks of Alzheimer’s disease (AD) and are primarily composed of aggregates of hyperphosphorylated forms of the microtubule associated protein tau. It is likely that an imbalance of kinase and phosphatase activities leads to the abnormal...

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Detalhes bibliográficos
Main Authors: Boutajangout, Allal, Sigurdsson, Einar M., Krishnamurthy, Pavan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445026/
https://ncbi.nlm.nih.gov/pubmed/21679154
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