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Immunotherapy Targeting Pathological Tau Prevents Cognitive Decline in a New Tangle Mouse Model

Harnessing the immune system to clear protein aggregates is emerging as a promising approach to treat various neurodegenerative diseases. In Alzheimer's disease (AD), several clinical trials are ongoing using active and passive immunotherapy targeting the amyloid-β (Aβ) peptide. Limited emphasi...

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Hlavní autoři: Boutajangout, Allal, Quartermain, David, Sigurdsson, Einar M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135981/
https://ncbi.nlm.nih.gov/pubmed/21147995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4363-10.2010
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