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Immunotherapy Targeting Pathological Tau Conformers in a Tangle Mouse Model Reduces Brain Pathology with Associated Functional Improvements

Immunotherapies for various neurodegenerative diseases have recently emerged as a promising approach for clearing pathological protein conformers in these disorders. This type of treatment has not been assessed in models that develop neuronal tau aggregates as observed in frontotemporal dementia and...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Asuni, Ayodeji A., Boutajangout, Allal, Quartermain, David, Sigurdsson, Einar M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672191/
https://ncbi.nlm.nih.gov/pubmed/17715348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2361-07.2007
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