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Immunotherapy Targeting Pathological Tau Conformers in a Tangle Mouse Model Reduces Brain Pathology with Associated Functional Improvements

Immunotherapies for various neurodegenerative diseases have recently emerged as a promising approach for clearing pathological protein conformers in these disorders. This type of treatment has not been assessed in models that develop neuronal tau aggregates as observed in frontotemporal dementia and...

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Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Asuni, Ayodeji A., Boutajangout, Allal, Quartermain, David, Sigurdsson, Einar M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672191/
https://ncbi.nlm.nih.gov/pubmed/17715348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2361-07.2007
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