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Two Novel Tau Antibodies Targeting the 396/404 Region Are Primarily Taken Up by Neurons and Reduce Tau Protein Pathology

Aggregated Tau proteins are hallmarks of Alzheimer disease and other tauopathies. Recent studies from our group and others have demonstrated that both active and passive immunizations reduce Tau pathology and prevent cognitive decline in transgenic mice. To determine the efficacy and safety of targe...

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Detalhes bibliográficos
Main Authors: Gu, Jiaping, Congdon, Erin E., Sigurdsson, Einar M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829157/
https://ncbi.nlm.nih.gov/pubmed/24089520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.494922
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