Early Effects of Aβ Oligomers on Dendritic Spine Dynamics and Arborization in Hippocampal Neurons

Alzheimer’s disease (AD) is a neurodegenerative disorder that leads to impaired memory and cognitive deficits. Spine loss as well as changes in spine morphology correlates with cognitive impairment in this neurological disorder. Many studies in animal models and ex vivo cultures indicate that amyloi...

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Détails bibliographiques
Publié dans:Front Synaptic Neurosci
Auteurs principaux: Ortiz-Sanz, Carolina, Gaminde-Blasco, Adhara, Valero, Jorge, Bakota, Lidia, Brandt, Roland, Zugaza, José L., Matute, Carlos, Alberdi, Elena
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029715/
https://ncbi.nlm.nih.gov/pubmed/32116638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2020.00002
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