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Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons

The microtubule-associated phosphoprotein tau regulates microtubule dynamics and is involved in neurodegenerative diseases collectively called tauopathies. It is generally believed that the vast majority of tau molecules decorate axonal microtubules, thereby stabilizing them. However, it is an open...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Janning, Dennis, Igaev, Maxim, Sündermann, Frederik, Brühmann, Jörg, Beutel, Oliver, Heinisch, Jürgen J., Bakota, Lidia, Piehler, Jacob, Junge, Wolfgang, Brandt, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230615/
https://ncbi.nlm.nih.gov/pubmed/25165145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1099
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