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Annexins A2 and A6 interact with the extreme N terminus of tau and thereby contribute to tau's axonal localization

During neuronal development, the microtubule-associated protein tau becomes enriched in the axon, where it remains concentrated in the healthy brain. In tauopathies such as Alzheimer's disease, tau redistributes from the axon to the somatodendritic compartment. However, the cellular mechanism t...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Gauthier-Kemper, Anne, Suárez Alonso, María, Sündermann, Frederik, Niewidok, Benedikt, Fernandez, Maria-Pilar, Bakota, Lidia, Heinisch, Jürgen Josef, Brandt, Roland
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971446/
https://ncbi.nlm.nih.gov/pubmed/29636414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000490
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