Loading...

Effect of Phosphorylation and O-GlcNAcylation on Proline-Rich Domains of Tau

Microtubule associated protein Tau (MAPT) is a phospho-protein within neurons of the brain. Aggregation of tau is the leading cause of tauopathies such as Alzheimer’s disease. Tau undergoes several post-translational modifications of which phosphorylation and O-GlcNAcylation are key chemical modific...

Full description

Saved in:
Bibliographic Details
Published in:J Phys Chem B
Main Authors: Rani, Lata, Mittal, Jeetain, Mallajosyula, Sairam S.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459333/
https://ncbi.nlm.nih.gov/pubmed/32065850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b11720
Tags: Add Tag
No Tags, Be the first to tag this record!