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Effect of Phosphorylation and O-GlcNAcylation on Proline-Rich Domains of Tau
Microtubule associated protein Tau (MAPT) is a phospho-protein within neurons of the brain. Aggregation of tau is the leading cause of tauopathies such as Alzheimer’s disease. Tau undergoes several post-translational modifications of which phosphorylation and O-GlcNAcylation are key chemical modific...
Gardado en:
| Publicado en: | J Phys Chem B |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7459333/ https://ncbi.nlm.nih.gov/pubmed/32065850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b11720 |
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