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Effect of Phosphorylation and O-GlcNAcylation on Proline-Rich Domains of Tau
Microtubule associated protein Tau (MAPT) is a phospho-protein within neurons of the brain. Aggregation of tau is the leading cause of tauopathies such as Alzheimer’s disease. Tau undergoes several post-translational modifications of which phosphorylation and O-GlcNAcylation are key chemical modific...
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| Udgivet i: | J Phys Chem B |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7459333/ https://ncbi.nlm.nih.gov/pubmed/32065850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b11720 |
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