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Direct Crosstalk Between O-GlcNAcylation and Phosphorylation of Tau Protein Investigated by NMR Spectroscopy

The formation of intraneuronal fibrillar inclusions of tau protein is associated with several neurodegenerative diseases referred to as tauopathies including Alzheimer's disease (AD). A common feature of these pathologies is hyperphosphorylation of tau, the main component of fibrillar assemblie...

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Bibliografske podrobnosti
izdano v:Front Endocrinol (Lausanne)
Main Authors: Bourré, Gwendoline, Cantrelle, François-Xavier, Kamah, Amina, Chambraud, Béatrice, Landrieu, Isabelle, Smet-Nocca, Caroline
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198643/
https://ncbi.nlm.nih.gov/pubmed/30386294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00595
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