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Direct Crosstalk Between O-GlcNAcylation and Phosphorylation of Tau Protein Investigated by NMR Spectroscopy

The formation of intraneuronal fibrillar inclusions of tau protein is associated with several neurodegenerative diseases referred to as tauopathies including Alzheimer's disease (AD). A common feature of these pathologies is hyperphosphorylation of tau, the main component of fibrillar assemblie...

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Опубликовано в: :Front Endocrinol (Lausanne)
Главные авторы: Bourré, Gwendoline, Cantrelle, François-Xavier, Kamah, Amina, Chambraud, Béatrice, Landrieu, Isabelle, Smet-Nocca, Caroline
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198643/
https://ncbi.nlm.nih.gov/pubmed/30386294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00595
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