Secreted Amyloid Precursor Protein β and Secreted Amyloid Precursor Protein α Induce Axon Outgrowth In Vitro through Egr1 Signaling Pathway

BACKGROUND: sAPPα released after α secretase cleavage of Amyloid Precursor Protein (APP) has several functions including the stimulation of neurite outgrowth although detailed morphometric analysis has not been done. Two domains involved in this function have been described and are present in sAPPβ...

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Main Authors: Chasseigneaux, Stéphanie, Dinc, Levent, Rose, Christiane, Chabret, Claude, Coulpier, Fanny, Topilko, Piotr, Mauger, Gweltas, Allinquant, Bernadette
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029320/
https://ncbi.nlm.nih.gov/pubmed/21298006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016301
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