Amyloid Precursor Protein Regulates Netrin-1-mediated Commissural Axon Outgrowth

The multifunctional protein netrin-1 was initially discovered as the main attractive cue for commissural axon guidance by acting through its receptor DCC. Recently, we have shown that netrin-1 also interacts with the orphan transmembrane receptor amyloid precursor protein (APP). APP is cleaved by pr...

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Bibliographic Details
Main Authors: Rama, Nicolas, Goldschneider, David, Corset, Véronique, Lambert, Jérémy, Pays, Laurent, Mehlen, Patrick
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Neurobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436182/
https://ncbi.nlm.nih.gov/pubmed/22782894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.324780
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