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Floor plate-derived netrin-1 is dispensable for commissural axon guidance
Netrin-1 is an evolutionarily conserved secreted extracellular matrix protein discovered using genetic and biochemical screens for its role in axon guidance at the central nervous system (CNS) midline1,2. Netrin-1 is expressed by cells localized at CNS midline, such as the floor plate in vertebrate...
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Publicado no: | Nature |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5438598/ https://ncbi.nlm.nih.gov/pubmed/28445456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22331 |
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