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DSCAM functions as a netrin receptor in commissural axon pathfinding

Down syndrome cell adhesion molecule (DSCAM) is required for axon guidance and dendrite arborization. How DSCAM functions in vertebrates is not well understood. Here we show that DSCAM is expressed on commissural axons and interacts with Netrin-1, a prototypical guidance cue for commissural axons. T...

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Main Authors: Liu, Guofa, Li, Weiquan, Wang, Lei, Kar, Amar, Guan, Kun-Liang, Rao, Yi, Wu, Jane Y.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650370/
https://ncbi.nlm.nih.gov/pubmed/19196994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811083106
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