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DSCAM functions as a netrin receptor in commissural axon pathfinding

Down syndrome cell adhesion molecule (DSCAM) is required for axon guidance and dendrite arborization. How DSCAM functions in vertebrates is not well understood. Here we show that DSCAM is expressed on commissural axons and interacts with Netrin-1, a prototypical guidance cue for commissural axons. T...

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Detalhes bibliográficos
Main Authors: Liu, Guofa, Li, Weiquan, Wang, Lei, Kar, Amar, Guan, Kun-Liang, Rao, Yi, Wu, Jane Y.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650370/
https://ncbi.nlm.nih.gov/pubmed/19196994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811083106
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