Neuroprotective Secreted Amyloid Precursor Protein Acts by Disrupting Amyloid Precursor Protein Dimers

The amyloid precursor protein (APP) is implied both in cell growth and differentiation and in neurodegenerative processes in Alzheimer disease. Regulated proteolysis of APP generates biologically active fragments such as the neuroprotective secreted ectodomain sAPPα and the neurotoxic β-amyloid pept...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Gralle, Matthias, Botelho, Michelle Gralle, Wouters, Fred S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Molecular Basis of Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685684/
https://ncbi.nlm.nih.gov/pubmed/19336403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808755200
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky