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Flotillin-Dependent Clustering of the Amyloid Precursor Protein Regulates Its Endocytosis and Amyloidogenic Processing in Neurons

The flotillins/reggie proteins are associated with noncaveolar membrane microdomains and have been implicated in the regulation of a clathrin- and caveolin-independent endocytosis pathway. Endocytosis is required for the amyloidogenic processing of the amyloid precursor protein (APP) and thus to ini...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Schneider, Anja, Rajendran, Lawrence, Honsho, Masanori, Gralle, Matthias, Donnert, Gerald, Wouters, Fred, Hell, Stefan W., Simons, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670660/
https://ncbi.nlm.nih.gov/pubmed/18337418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5345-07.2008
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