What is the role of amyloid precursor protein dimerization?

Extensive research efforts have been conducted over the past decades to understand the processing of the Amyloid Precursor Protein (APP). APP cleavage leads to the production of the β-amyloid peptide (Aβ), which is the major constituent of the amyloid core of senile plaques found in the brains of pa...

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Hlavní autoři: Ben Khalifa, Naouel, Van Hees, Joanne, Tasiaux, Bernadette, Huysseune, Sandra, Smith, Steven O., Constantinescu, Stefan N., Octave, Jean-Noël, Kienlen-Campard, Pascal
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2010
Témata:
Special Focus: The Role of Transmembrane Domains in Adhesion
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900624/
https://ncbi.nlm.nih.gov/pubmed/20400860
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