What is the role of amyloid precursor protein dimerization?

Extensive research efforts have been conducted over the past decades to understand the processing of the Amyloid Precursor Protein (APP). APP cleavage leads to the production of the β-amyloid peptide (Aβ), which is the major constituent of the amyloid core of senile plaques found in the brains of pa...

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Auteurs principaux: Ben Khalifa, Naouel, Van Hees, Joanne, Tasiaux, Bernadette, Huysseune, Sandra, Smith, Steven O., Constantinescu, Stefan N., Octave, Jean-Noël, Kienlen-Campard, Pascal
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2010
Sujets:
Special Focus: The Role of Transmembrane Domains in Adhesion
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900624/
https://ncbi.nlm.nih.gov/pubmed/20400860
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