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Regulation of β cleavage of amyloid precursor protein

Alzheimer’s disease ranks the first cause for senile dementia. The amyloid cascade is proposed to contribute to the pathogenesis of this disease. In this cascade, amyloid β peptide (Aβ) is produced through a sequential cleavage of amyloid precursor protein (APP) by β and γ secretases, while its clea...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurosci Bull
Prif Awduron: Wang, Jun-Feng, Lu, Rui, Wang, Yi-Zheng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560349/
https://ncbi.nlm.nih.gov/pubmed/20882069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-010-0515-1
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