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Regulation of β cleavage of amyloid precursor protein
Alzheimer’s disease ranks the first cause for senile dementia. The amyloid cascade is proposed to contribute to the pathogenesis of this disease. In this cascade, amyloid β peptide (Aβ) is produced through a sequential cleavage of amyloid precursor protein (APP) by β and γ secretases, while its clea...
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| Publicado no: | Neurosci Bull |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5560349/ https://ncbi.nlm.nih.gov/pubmed/20882069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-010-0515-1 |
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