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Regulation of β cleavage of amyloid precursor protein

Alzheimer’s disease ranks the first cause for senile dementia. The amyloid cascade is proposed to contribute to the pathogenesis of this disease. In this cascade, amyloid β peptide (Aβ) is produced through a sequential cleavage of amyloid precursor protein (APP) by β and γ secretases, while its clea...

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Bibliografiske detaljer
Udgivet i:Neurosci Bull
Main Authors: Wang, Jun-Feng, Lu, Rui, Wang, Yi-Zheng
Format: Artigo
Sprog:Inglês
Udgivet: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560349/
https://ncbi.nlm.nih.gov/pubmed/20882069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-010-0515-1
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