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Regulation of β cleavage of amyloid precursor protein
Alzheimer’s disease ranks the first cause for senile dementia. The amyloid cascade is proposed to contribute to the pathogenesis of this disease. In this cascade, amyloid β peptide (Aβ) is produced through a sequential cleavage of amyloid precursor protein (APP) by β and γ secretases, while its clea...
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| Udgivet i: | Neurosci Bull |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5560349/ https://ncbi.nlm.nih.gov/pubmed/20882069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-010-0515-1 |
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