Synthesis of a Macrocycle Based on Linked Amino Acid Mimetics (LAAM)

We report the synthesis of a macrocycle utilizing a novel framework of standard amino acids in combination with subunits that we have named as Linked Amino Acid Mimetics (LAAM’s). Macrocycles based on the LAAM concept provide both a peptide targeting region and two independently variable functional...

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Bibliografiske detaljer
Main Authors: Maxwell, David S., Sun, Duoli, Peng, Zhenghong, Martin, Diana V., Bhanu Prasad, Basvoju A., Bornmann, William G.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125026/
https://ncbi.nlm.nih.gov/pubmed/25110365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.08.041
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