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Development of sigma-1 (σ(1)) receptor fluorescent ligands as versatile tools to study σ(1) receptors(✩)

Despite their controversial physiology, sigma-1 (σ(1)) receptors are intriguing targets for the development of therapeutic agents for central nervous system diseases. With the aim of providing versatile pharmacological tools to study σ(1) receptors, we developed three σ(1) fluorescent tracers by fun...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Abate, Carmen, Riganti, Chiara, Pati, Maria Laura, Ghigo, Dario, Berardi, Francesco, Mavlyutov, Timur, Guo, Lian-Wang, Ruoho, Arnold
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755300/
https://ncbi.nlm.nih.gov/pubmed/26717207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.12.014
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