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Development of sigma-1 (σ(1)) receptor fluorescent ligands as versatile tools to study σ(1) receptors(✩)

Despite their controversial physiology, sigma-1 (σ(1)) receptors are intriguing targets for the development of therapeutic agents for central nervous system diseases. With the aim of providing versatile pharmacological tools to study σ(1) receptors, we developed three σ(1) fluorescent tracers by fun...

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Publicado en:Eur J Med Chem
Autores principales: Abate, Carmen, Riganti, Chiara, Pati, Maria Laura, Ghigo, Dario, Berardi, Francesco, Mavlyutov, Timur, Guo, Lian-Wang, Ruoho, Arnold
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755300/
https://ncbi.nlm.nih.gov/pubmed/26717207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.12.014
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