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Antitumor Agents 280. Multidrug Resistance-Selective Desmosdumotin B Analogues

6,6,8-Triethyldesmosdumotin B (2) was discovered as a MDR–selective flavonoid with significant in vitro anticancer activity against a multi-drug resistant (MDR) cell line (KB-VIN) but without activity against the parent cells (KB). Additional 2-analogues were synthesized and evaluated to determine t...

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Detalhes bibliográficos
Main Authors: Nakagawa-Goto, Kyoko, Chang, Po-Cheng, Lai, Chin-Yu, Hung, Hsin-Yi, Chen, Tzu-Hsuan, Wu, Pei-Chi, Zhu, Hao, Sedykh, Alexander, Bastow, Kenneth F., Lee, Kuo-Hsiung
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945214/
https://ncbi.nlm.nih.gov/pubmed/20735140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm100846r
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