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Antitumor Agents 280. Multidrug Resistance-Selective Desmosdumotin B Analogues
6,6,8-Triethyldesmosdumotin B (2) was discovered as a MDR–selective flavonoid with significant in vitro anticancer activity against a multi-drug resistant (MDR) cell line (KB-VIN) but without activity against the parent cells (KB). Additional 2-analogues were synthesized and evaluated to determine t...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2945214/ https://ncbi.nlm.nih.gov/pubmed/20735140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm100846r |
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