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Antitumor Agents 293. Non-toxic Dimethyl-4,4′-dimethoxy-5,6,5′,6′-dimethylenedioxybiphenyl-2,2′-dicarboxylate (DDB) Analogs Chemosensitize Multidrug Resistant Cancer Cells to Clinical Anticancer Drugs

Novel dimethyl-4,4′-dimethoxy-5,6,5′,6′-dimethylenedioxybiphenyl-2,2′-dicarboxylate (DDB) analogs were designed and synthesized to improve their chemosensitizing action on KBvin (vincristine resistant nasopharyngeal carcinoma) cells, a multi-drug resistant cell line over-expressing P-glycoprotein (P...

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Detalhes bibliográficos
Main Authors: Hung, Hsin-Yi, Ohkoshi, Emika, Goto, Masuo, Bastow, Kenneth F., Nakagawa-Goto, Kyoko, Lee, Kuo-Hsiung
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375343/
https://ncbi.nlm.nih.gov/pubmed/22612652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm300378k
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