Regulation of β-catenin by t-DARPP in upper gastrointestinal cancer cells

door Vangamudi, Bhavatarini, Zhu, Shoumin, Soutto, Mohammed, Belkhiri, Abbes, El-Rifai, Wael
Gepubliceerd in 2011

t-DARPP regulates phosphatidylinositol-3-kinase-dependent cell growth in breast cancer

door Vangamudi, Bhavatarini, Peng, Dun-Fa, Cai, Qiuyin, El-Rifai, Wael, Zheng, Wei, Belkhiri, Abbes
Gepubliceerd in 2010

Surface reengineering of RPA70N enables co-crystallization with an inhibitor of the RPA interaction motif of ATRIP

door Feldkamp, Michael D., Frank, Andreas O., Kennedy, J. Phillip, Patrone, James D., Vangamudi, Bhavatarini, Waterson, Alex G., Fesik, Stephen W., Chazin, Walter J.
Gepubliceerd in 2013

Discovery of Protein–Protein Interaction Inhibitors of Replication Protein A

door Patrone, James D., Kennedy, J. Phillip, Frank, Andreas O., Feldkamp, Michael D., Vangamudi, Bhavatarini, Pelz, Nicholas F., Rossanese, Olivia W., Waterson, Alex G., Chazin, Walter J., Fesik, Stephen W.
Gepubliceerd in 2013

Discovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A

door Frank, Andreas O., Vangamudi, Bhavatarini, Feldkamp, Michael D., Souza-Fagundes, Elaine M., Luzwick, Jessica W., Cortez, David, Olejniczak, Edward T., Waterson, Alex G., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Gepubliceerd in 2014

Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions Using a Fragment Linking Approach

door Frank, Andreas O., Feldkamp, Michael D., Kennedy, J. Phillip, Waterson, Alex G., Pelz, Nicholas F., Patrone, James D., Vangamudi, Bhavatarini, Camper, DeMarco V., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Gepubliceerd in 2013

Diphenylpyrazoles as Replication Protein A Inhibitors

door Waterson, Alex G., Kennedy, J. Phillip, Patrone, James D., Pelz, Nicholas F., Feldkamp, Michael D., Frank, Andreas O., Vangamudi, Bhavatarini, Souza-Fagundes, Elaine M., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Gepubliceerd in ACS Med Chem Lett (2014)

Identification and Optimization of Anthranilic Acid-Based Inhibitors of Replication Protein A

door Patrone, James D., Pelz, Nicholas F., Bates, Brittney S., Souza-Fagundes, Elaine M., Vangamudi, Bhavatarini, Camper, Demarco V., Kuznetsov, Alexey G., Browning, Carrie F., Feldkamp, Michael D., Frank, Andreas O., Gilston, Benjamin A., Olejniczak, Edward T., Rossanese, Olivia W., Waterson, Alex G., Chazin, Walter J., Fesik, Stephen W.
Gepubliceerd in ChemMedChem (2016)

Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery

door Zhan, Yanai, Kost-Alimova, Maria, Shi, Xi, Leo, Elisabetta, Bardenhagen, Jennifer P., Shepard, Hannah E., Appikonda, Srikanth, Vangamudi, Bhavatarini, Zhao, Shuping, Tieu, Trang N., Jiang, Shiming, Heffernan, Timothy P., Marszalek, Joseph R., Toniatti, Carlo, Draetta, Giulio, Tyler, Jessica, Barton, Michelle, Jones, Philip, Palmer, Wylie S., Geck Do, Mary K., Andersen, Jannik N.
Gepubliceerd in Epigenetics Chromatin (2015)

The SMARCA2/4 ATPase domain surpasses the bromodomain as a drug target in SWI/SNF mutant cancers: Insights from cDNA rescue and PFI-3 inhibitor studies

door Vangamudi, Bhavatarini, Paul, Thomas A., Shah, Parantu K., Kost-Alimova, Maria, Nottebaum, Lisa, Shi, Xi, Zhan, Yanai, Leo, Elisabetta, Mahadeshwar, Harshad S., Protopopov, Alexei, Futreal, Andrew, Tieu, Trang N., Peoples, Mike, Heffernan, Timothy P., Marszalek, Joseph R., Toniatti, Carlo, Petrocchi, Alessia, Verhelle, Dominique, Owen, Dafydd R., Draetta, Giulio, Jones, Philip, Palmer, Wylie S., Sharma, Shikhar, Andersen, Jannik N.
Gepubliceerd in Cancer Res (2015)

Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs

door Golder, Matthew R., Liu, Jenny, Andersen, Jannik N., Shipitsin, Michail V., Vohidov, Farrukh, Nguyen, Hung V.-T., Ehrlich, Deborah C., Huh, Sung Jin, Vangamudi, Bhavatarini, Economides, Kyriakos D., Neenan, Allison M., Ackley, James C., Baddour, Joelle, Paramasivan, Sattanathan, Brady, Samantha W., Held, Eric J., Reiter, Lawrence A., Saucier-Sawyer, Jennifer K., Kopesky, Paul W., Chickering, Donald E., Blume-Jensen, Peter, Johnson, Jeremiah A.
Gepubliceerd in Nat Biomed Eng (2018)

Design of BET Inhibitor Bottlebrush Prodrugs with Superior Efficacy and Devoid of Systemic Toxicities

door Vohidov, Farrukh, Andersen, Jannik N., Economides, Kyriakos D., Shipitsin, Michail V., Burenkova, Olga, Ackley, James C., Vangamudi, Bhavatarini, Nguyen, Hung V.-T., Gallagher, Nolan M., Shieh, Peyton, Golder, Matthew R., Liu, Jenny, Dahlberg, William K., Ehrlich, Deborah J. C., Kim, Julie, Kristufek, Samantha L., Jin Huh, Sung, Neenan, Allison M., Baddour, Joelle, Paramasivan, Sattanathan, de Stanchina, Elisa, Gaurab, KC, Turnquist, David J., Saucier-Sawyer, Jennifer K., Kopesky, Paul W., Brady, Samantha W., Jessel, Michael J., Reiter, Lawrence A., Chickering, Donald E., Johnson, Jeremiah A., Blume-Jensen, Peter
Gepubliceerd in J Am Chem Soc (2021)

PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma

door Giuliani, Virginia, Miller, Meredith A., Liu, Chiu-Yi, Hartono, Stella R., Class, Caleb A., Bristow, Christopher A., Suzuki, Erika, Sanz, Lionel A., Gao, Guang, Gay, Jason P., Feng, Ningping, Rose, Johnathon L., Tomihara, Hideo, Daniele, Joseph R., Peoples, Michael D., Bardenhagen, Jennifer P., Geck Do, Mary K., Chang, Qing E., Vangamudi, Bhavatarini, Vellano, Christopher, Ying, Haoqiang, Deem, Angela K., Do, Kim-Anh, Genovese, Giannicola, Marszalek, Joseph R., Kovacs, Jeffrey J., Kim, Michael, Fleming, Jason B., Guccione, Ernesto, Viale, Andrea, Maitra, Anirban, Emilia Di Francesco, M., Yap, Timothy A., Jones, Philip, Draetta, Giulio, Carugo, Alessandro, Chedin, Frederic, Heffernan, Timothy P.
Gepubliceerd in Nat Commun (2021)