Predicting the subcellular localization of viral proteins within a mammalian host cell

Por Scott, MS, Oomen, R, Thomas, DY, Hallett, MT
Publicado em 2006

Assay Format as a Critical Success Factor for Identification of Novel Inhibitor Chemotypes of Tissue-Nonspecific Alkaline Phosphatase from High-Throughput Screening

Por Chung, Thomas D.Y., Sergienko, Eduard, Millán, José Luis
Publicado em 2010

New p32/gC1qR Ligands for Targeted Tumor Drug Delivery()

Por Paasonen, Lauri, Sharma, Shweta, Braun, Gary B, Kotamraju, Venkata Ramana, Chung, Thomas D.Y., She, Zhigang, Sugahara, Kazuki N, Yliperttula, Marjo, Wu, Bainan, Pellecchia, Maurizio, Ruoslahti, Erkki, Teesalu, Tambet
Publicado no Chembiochem (2016)

TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases via cAMP/Gα(s) signaling

Por Masyuk, Tatyana V, Masyuk, Anatoliy I, Pisarello, Maria Lorenzo, Howard, Brynn N, Huang, Bing Q, Lee, Pui-Yuen, Fung, Xavier, Sergienko, Eduard, Ardesky, Robert J, Chung, Thomas DY, Pinkerton, Anthony B, LaRusso, Nicholas F
Publicado no Hepatology (2017)

Both HIV infected and uninfected cells express TRAILshort, which confers TRAIL resistance upon bystander cells within the microenvironment

Por Nie, Zilin, Aboulnasr, Fatma, Natesampillai, Sekar, Burke, Steve P., Krogman, Ashton, Bren, Gary D., Chung, Thomas D.Y., Anderson, Jeff R., Smart, Michele K., Katzmann, David J., Rajagopalan, Govindarajan, Cummins, Nathan W., Badley, Andrew D.
Publicado no J Immunol (2017)

An overview of the challenges in designing, integrating, and delivering BARD: a public chemical biology resource and query portal across multiple organizations, locations, and disc...

Por de Souza, Andrea, Bittker, Joshua, Lahr, David, Brudz, Steve, Chatwin, Simon, Oprea, Tudor I., Waller, Anna, Yang, Jeremy, Southall, Noel, Guha, Rajarshi, Schurer, Stephan, Vempati, Uma, Southern, Mark R., Dawson, Eric S., Clemons, Paul A., Chung, Thomas D.Y.
Publicado no J Biomol Screen (2014)

IDENTIFICATION OF THE GPR55 AGONIST BINDING SITE USING A NOVEL SET OF HIGH POTENCY GPR55 SELECTIVE LIGANDS

Por Kotsikorou, Evangelia, Madrigal, Karla E., Hurst, Dow P., Sharir, Haleli, Lynch, Diane L., Heynen-Genel, Susanne, Milan, Loribelle B., Chung, Thomas D.Y., Seltzman, Herbert H., Bai, Yushi, Caron, Marc G., Barak, Larry, Abood, Mary E., Reggio, Patricia H.
Publicado em 2011

Targeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptiv...

Por Zhao, Pingwei, Sharir, Haleli, Kapur, Ankur, Cowan, Alan, Geller, Ellen B., Adler, Martin W., Seltzman, Herbert H., Reggio, Patricia H., Heynen-Genel, Susanne, Sauer, Michelle, Chung, Thomas D.Y., Bai, Yushi, Chen, Wei, Caron, Marc G., Barak, Larry S., Abood, Mary E.
Publicado em 2010

ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse

Por Barak, Larry S., Bai, Yushi, Peterson, Sean M., Evron, Tama, Urs, Nikhil M., Peddibhotla, Satyamaheshwar, Hedrick, Michael P., Hershberger, Paul, Maloney, Patrick, Chung, Thomas D.Y., Rodriguiz, R. M., Wetsel, W.C., Thomas, James B., Hanson, Glen R., Pinkerton, Anthony B., Caron, Marc G.
Publicado no ACS Chem Biol (2016)

IDENTIFICATION OF THE GPR55 ANTAGONIST BINDING SITE USING A NOVEL SET OF HIGH POTENCY GPR55 SELECTIVE LIGANDS

Por Kotsikorou, Evangelia, Sharir, Haleli, Shore, Derek M., Hurst, Dow P., Lynch, Diane L., Madrigal, Karla E., Heynen-Genel, Susanne, Milan, Loribelle B., Chung, Thomas D.Y., Seltzman, Herbert H., Bai, Yushi, Caron, Marc G., Barak, Larry S., Croatt, Mitchell P., Abood, Mary E., Reggio, Patricia H.
Publicado em 2013

Design of High Throughput Screening Assays and Identification of a SUMO1-Specific Small Molecule Chemotype Targeting the SUMO-Interacting Motif-Binding Surface

Por Alontaga, Aileen Y., Li, Yifei, Chen, Chih-Hong, Ma, Chen-Ting, Malany, Siobhan, Key, Danielle E., Sergienko, Eduard, Sun, Qing, Whipple, David A., Matharu, Daljit S., Li, Baozong, Vega, Ramir, Li, Yi-Jia, Schoenen, Frank J., Blagg, Brian S. J., Chung, Thomas D.Y., Chen, Yuan
Publicado no ACS Comb Sci (2015)

Inhibition of Hematopoietic Protein Tyrosine Phosphatase Augments and Prolongs ERK1/2 and p38 Activation

Por Sergienko, Eduard, Xu, Jian, Liu, Wallace H., Dahl, Russell, Critton, David A., Su, Ying, Brown, Brock T., Chan, Xochella, Yang, Li, Bobkova, Ekaterina V., Vasile, Stefan, Yuan, Hongbin, Rascon, Justin, Colayco, Sharon, Sidique, Shyama, Cosford, Nicholas D.P., Chung, Thomas D.Y., Mustelin, Tomas, Page, Rebecca, Lombroso, Paul J., Tautz, Lutz
Publicado em 2011

Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11

Por Li, Jing, Yakushi, Tanya, Parlati, Francesco, Mackinnon, Andrew L., Perez, Christian, Ma, Yuyong, Carter, Kyle P., Colayco, Sharon, Magnuson, Gavin, Brown, Brock, Nguyen, Kevin, Vasile, Stefan, Suyama, Eigo, Smith, Layton H., Sergienko, Eduard, Pinkerton, Anthony B., Chung, Thomas D.Y., Palmer, Amy E., Pass, Ian, Hess, Sonja, Cohen, Seth M., Deshaies, Raymond J.
Publicado no Nat Chem Biol (2017)

Identification of a Selective Inhibitor of Murine Intestinal Alkaline Phosphatase (ML260) by Concurrent Ultra-High Throughput Screening against Human and Mouse Isozymes

Por Ardecky, Robert J., Bobkova, Ekaterina V., Kiffer-Moreira, Tina, Brown, Brock, Ganji, Santhi, Zou, Jiwen, Pass, Ian, Narisawa, Sonoko, Iano, Flávia Godoy, Rosenstein, Craig, Cheltsov, Anton, Rascon, Justin, Hedrick, Michael, Gasior, Carlton, Forster, Anita, Shi, Shenghua, Dahl, Russell, Vasile, Stefan, Su, Ying, Sergienko, Eduard, Chung, Thomas D.Y., Kaunitz, Jonathan, Hoylaerts, Marc F., Pinkerton, Anthony B., Millán, José Luis
Publicado em 2013

Diabetes reversal by inhibition of the low molecular weight tyrosine phosphatase

Por Stanford, Stephanie M, Aleshin, Alexander E, Zhang, Vida, Ardecky, Robert J, Hedrick, Michael P, Zou, Jiwen, Ganji, Santhi R., Bliss, Matthew R, Yamamoto, Fusayo, Bobkov, Andrey A., Kiselar, Janna, Liu, Yingge, Cadwell, Gregory W, Khare, Shilpi, Yu, Jinghua, Barquilla, Antonio, Chung, Thomas DY, Mustelin, Tomas, Schenk, Simon, Bankston, Laurie A, Liddington, Robert C, Pinkerton, Anthony B, Bottini, Nunzio
Publicado no Nat Chem Biol (2017)

Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6- phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3...

Por Preuss, Janina, Maloney, Patrick, Peddibhotla, Satyamaheshwar, Hedrick, Michael P., Hershberger, Paul, Gosalia, Palak, Milewski, Monika, Li, Yujie Linda, Sugarman, Eliot, Hood, Becky, Suyama, Eigo, Nguyen, Kevin, Vasile, Stefan, Sergienko, Eduard, Mangravita-Novo, Arianna, Vicchiarelli, Michael, McAnally, Danielle, Smith, Layton H., Roth, Gregory P., Diwan, Jena, Chung, Thomas D.Y., Jortzik, Esther, Rahlfs, Stefan, Becker, Katja, Pinkerton, Anthony B., Bode, Lars
Publicado em 2012

DUSP3 Phosphatase Deficiency or Inhibition Limit Platelet Activation and Arterial Thrombosis

Por Musumeci, Lucia, Kuijpers, Marijke J, Gilio, Karen, Hego, Alexandre, Théâtre, Emilie, Maurissen, Lisbeth, Vandereyken, Maud, Diogo, Catia V, Lecut, Christelle, Guilmain, William, Bobkova, Ekaterina V, Eble, Johannes A., Dahl, Russell, Drion, Pierre, Rascon, Justin, Mostofi, Yalda, Yuan, Hongbin, Sergienko, Eduard, Chung, Thomas DY, Thiry, Marc, Senis, Yotis, Moutschen, Michel, Mustelin, Tomas, Lancellotti, Patrizio, Heemskerk, Johan WM, Tautz, Lutz, Oury, Cécile, Rahmouni, Souad
Publicado no Circulation (2014)

Advancing Biological Understanding and Therapeutics Discovery with Small Molecule Probes

Por Schreiber, Stuart L., Kotz, Joanne D., Li, Min, Aubé, Jeffrey, Austin, Christopher P., Reed, John C., Rosen, Hugh, White, E. Lucile, Sklar, Larry A., Lindsley, Craig W., Alexander, Benjamin R., Bittker, Joshua A., Clemons, Paul A., de Souza, Andrea, Foley, Michael A., Palmer, Michelle, Shamji, Alykhan F., Wawer, Mathias J., McManus, Owen, Wu, Meng, Zou, Beiyan, Yu, Haibo, Golden, Jennifer E., Schoenen, Frank J., Simeonov, Anton, Jadhav, Ajit, Jackson, Michael R., Pinkerton, Anthony B., Chung, Thomas D.Y., Griffin, Patrick R., Cravatt, Benjamin F., Hodder, Peter S., Roush, William R., Roberts, Edward, Chung, Dong-Hoon, Jonsson, Colleen B., Noah, James W., Severson, William E., Ananthan, Subramaniam, Edwards, Bruce, Oprea, Tudor I., Conn, P. Jeffrey, Hopkins, Corey R., Wood, Michael R., Stauffer, Shaun R., Emmitte, Kyle A.
Publicado no Cell (2015)