Discovery of PDK1 Kinase Inhibitors with a Novel Mechanism of Action by Ultrahigh Throughput Screening

Por Bobkova, Ekaterina V., Weber, Michael J., Xu, Zangwei, Zhang, Yan-Ling, Jung, Joon, Blume-Jensen, Peter, Northrup, Alan, Kunapuli, Priya, Andersen, Jannik N., Kariv, Ilona
Publicado em 2010

Identification of Direct Target Engagement Biomarkers for Kinase-Targeted Therapeutics

Por Paweletz, Cloud P., Andersen, Jannik N., Pollock, Roy, Nagashima, Kumiko, Hayashi, Mansuo L., Yu, Shangshuan U., Guo, Hongbo, Bobkova, Ekaterina V., Xu, Zangwei, Northrup, Alan, Blume-Jensen, Peter, Hendrickson, Ronald C., Chi, An
Publicado em 2011

Identification of Novel Inhibitors of Bacterial Translation Elongation Factors

Por Jayasekera, Maithri M. K., Onheiber, Keysha, Keith, John, Venkatesan, Hariharan, Santillan, Alejandro, Stocking, Emily M., Tang, Liu, Miller, Jennifer, Gomez, Leslie, Rhead, Brooke, Delcamp, Tavner, Huang, Shaoming, Wolin, Ronald, Bobkova, Ekaterina V., Shaw, Karen Joy
Publicado em 2005

Inhibition of the Hematopoietic Protein Tyrosine Phosphatase by Phenoxyacetic Acids

Por Bobkova, Ekaterina V., Liu, Wallace H., Colayco, Sharon, Rascon, Justin, Vasile, Stefan, Gasior, Carlton, Critton, David A., Chan, Xochella, Dahl, Russell, Su, Ying, Sergienko, Eduard, Chung, Thomas D. Y., Mustelin, Tomas, Page, Rebecca, Tautz, Lutz
Publicado em 2010

Inhibition of Hematopoietic Protein Tyrosine Phosphatase Augments and Prolongs ERK1/2 and p38 Activation

Por Sergienko, Eduard, Xu, Jian, Liu, Wallace H., Dahl, Russell, Critton, David A., Su, Ying, Brown, Brock T., Chan, Xochella, Yang, Li, Bobkova, Ekaterina V., Vasile, Stefan, Yuan, Hongbin, Rascon, Justin, Colayco, Sharon, Sidique, Shyama, Cosford, Nicholas D.P., Chung, Thomas D.Y., Mustelin, Tomas, Page, Rebecca, Lombroso, Paul J., Tautz, Lutz
Publicado em 2011

Identification of a Selective Inhibitor of Murine Intestinal Alkaline Phosphatase (ML260) by Concurrent Ultra-High Throughput Screening against Human and Mouse Isozymes

Por Ardecky, Robert J., Bobkova, Ekaterina V., Kiffer-Moreira, Tina, Brown, Brock, Ganji, Santhi, Zou, Jiwen, Pass, Ian, Narisawa, Sonoko, Iano, Flávia Godoy, Rosenstein, Craig, Cheltsov, Anton, Rascon, Justin, Hedrick, Michael, Gasior, Carlton, Forster, Anita, Shi, Shenghua, Dahl, Russell, Vasile, Stefan, Su, Ying, Sergienko, Eduard, Chung, Thomas D.Y., Kaunitz, Jonathan, Hoylaerts, Marc F., Pinkerton, Anthony B., Millán, José Luis
Publicado em 2013

DUSP3 Phosphatase Deficiency or Inhibition Limit Platelet Activation and Arterial Thrombosis

Por Musumeci, Lucia, Kuijpers, Marijke J, Gilio, Karen, Hego, Alexandre, Théâtre, Emilie, Maurissen, Lisbeth, Vandereyken, Maud, Diogo, Catia V, Lecut, Christelle, Guilmain, William, Bobkova, Ekaterina V, Eble, Johannes A., Dahl, Russell, Drion, Pierre, Rascon, Justin, Mostofi, Yalda, Yuan, Hongbin, Sergienko, Eduard, Chung, Thomas DY, Thiry, Marc, Senis, Yotis, Moutschen, Michel, Mustelin, Tomas, Lancellotti, Patrizio, Heemskerk, Johan WM, Tautz, Lutz, Oury, Cécile, Rahmouni, Souad
Publicado no Circulation (2014)

Genetic and Pharmacological Inhibition of PDK1 in Cancer Cells: CHARACTERIZATION OF A SELECTIVE ALLOSTERIC KINASE INHIBITOR

Por Nagashima, Kumiko, Shumway, Stuart D., Sathyanarayanan, Sriram, Chen, Albert H., Dolinski, Brian, Xu, Youyuan, Keilhack, Heike, Nguyen, Thi, Wiznerowicz, Maciej, Li, Lixia, Lutterbach, Bart A., Chi, An, Paweletz, Cloud, Allison, Timothy, Yan, Youwei, Munshi, Sanjeev K., Klippel, Anke, Kraus, Manfred, Bobkova, Ekaterina V., Deshmukh, Sujal, Xu, Zangwei, Mueller, Uwe, Szewczak, Alexander A., Pan, Bo-Sheng, Richon, Victoria, Pollock, Roy, Blume-Jensen, Peter, Northrup, Alan, Andersen, Jannik N.
Publicado em 2011