Design, synthesis and evaluation of monovalent Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP

Por González-López, Marcos, Welsh, Kate, Finlay, Darren, Ardecky, Robert J., Ganji, Santhi Reddy, Su, Ying, Teriete, Peter, Mace, Peter D., Riedl, Stefan J., Vuori, Kristiina, Reed, John C., Cosford, Nicholas D. P.
Publicado em 2011

Design, synthesis and evaluation of inhibitor of apoptosis protein (IAP) antagonists that are highly selective for the BIR2 domain of XIAP

Por Ardecky, Robert J., Welsh, Kate, Finlay, Darren, Lee, Pooi San, González-López, Marcos, Reddy Ganji, Santhi, Ravanan, Palaniyandi, Mace, Peter D., Riedl, Stefan J., Vuori, Kristiina, Reed, John C., Cosford, Nicholas D. P.
Publicado em 2013

Small-molecule IAP antagonists sensitize cancer cells to TRAIL-induced apoptosis: Roles of XIAP and cIAPs

Por Finlay, Darren, Vamos, Mitchell, González-López, Marcos, Ardecky, Robert J., Ganji, Santhi Reddy, Yuan, Hongbin, Su, Ying, Cooley, Trina R., Hauser, Curt T., Welsh, Kate, Reed, John C., Cosford, Nicholas D. P., Vuori, Kristiina
Publicado em 2013

Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis

Por Welsh, Kate, Milutinovic, Snezana, Ardecky, Robert J., Gonzalez-Lopez, Marcos, Ganji, Santhi Reddy, Teriete, Peter, Finlay, Darren, Riedl, Stefan, Matsuzawa, Shu-ichi, Pinilla, Clemencia, Houghten, Richard, Vuori, Kristiina, Reed, John C., Cosford, Nicholas D. P.
Publicado no PLoS One (2016)

Expedient Synthesis of Highly Potent Antagonists of Inhibitor of Apoptosis Proteins (IAPs) with Unique Selectivity for ML-IAP

Por Vamos, Mitchell, Welsh, Kate, Finlay, Darren, Lee, Pooi San, Mace, Peter D., Snipas, Scott J., Gonzalez, Monica L., Ganji, Santhi Reddy, Ardecky, Robert J., Riedl, Stefan J., Salvesen, Guy S., Vuori, Kristiina, Reed, John C., Cosford, Nicholas D. P.
Publicado em 2013

Identification of a Selective Inhibitor of Murine Intestinal Alkaline Phosphatase (ML260) by Concurrent Ultra-High Throughput Screening against Human and Mouse Isozymes

Por Ardecky, Robert J., Bobkova, Ekaterina V., Kiffer-Moreira, Tina, Brown, Brock, Ganji, Santhi, Zou, Jiwen, Pass, Ian, Narisawa, Sonoko, Iano, Flávia Godoy, Rosenstein, Craig, Cheltsov, Anton, Rascon, Justin, Hedrick, Michael, Gasior, Carlton, Forster, Anita, Shi, Shenghua, Dahl, Russell, Vasile, Stefan, Su, Ying, Sergienko, Eduard, Chung, Thomas D.Y., Kaunitz, Jonathan, Hoylaerts, Marc F., Pinkerton, Anthony B., Millán, José Luis
Publicado em 2013

Diabetes reversal by inhibition of the low molecular weight tyrosine phosphatase

Por Stanford, Stephanie M, Aleshin, Alexander E, Zhang, Vida, Ardecky, Robert J, Hedrick, Michael P, Zou, Jiwen, Ganji, Santhi R., Bliss, Matthew R, Yamamoto, Fusayo, Bobkov, Andrey A., Kiselar, Janna, Liu, Yingge, Cadwell, Gregory W, Khare, Shilpi, Yu, Jinghua, Barquilla, Antonio, Chung, Thomas DY, Mustelin, Tomas, Schenk, Simon, Bankston, Laurie A, Liddington, Robert C, Pinkerton, Anthony B, Bottini, Nunzio
Publicado no Nat Chem Biol (2017)