High Throughput Synthesis of 2,3,6-Trisubstituted-5,6-Dihydroimidazo[2,1-b]thiazole Derivatives

par Li, Yangmei, Giulianotti, Marc, Houghten, Richard A.
Publié 2011

Macrolactonization of Peptide Thioesters Catalyzed by Imidazole and Its Application in the Synthesis of Kahalalide B and Analogues

par Li, Yangmei, Giulionatti, Marc, Houghten, Richard A.
Publié 2010

A Facile Approach to the Synthesis of 3,4-Disubstituted-2-Aminothiazolium Derivatives through the Use of A “Volatilizable” Support

par Li, Yangmei, Giulianotti, Marc, Houghten, Richard A.
Publié 2010

In vitro and direct in vivo testing of mixture-based combinatorial libraries for the identification of highly active and specific opiate ligands

par Houghten, Richard A., Dooley, Colette T., Appel, Jon R.
Publié 2006

One-Pot High-Throughput Synthesis of β-Turn Cyclic Peptidomimetics via “Volatilizable” Supports

par Li, Yangmei, Yu, Yongping, Giulianotti, Marc, Houghten, Richard A.
Publié 2009

High Throughput Synthesis of Peptide α-Thioesters Through the Use of “Volatilizable” Support

par Li, Yangmei, Yu, Yongping, Giulianotti, Marc, Houghten, Richard A.
Publié 2008

Antibodies of predetermined specificity detect two retroviral oncogene products and inhibit their kinase activities

par Sen, Stacy, Houghten, Richard A., Sherr, Charles J., Sen, Arup
Publié 1983

Identification of B Cell and T Cell Epitopes Using Synthetic Peptide Combinatorial Libraries

par Pinilla, Clemencia, Appel, Jon R., Judkowski, Valeria, Houghten, Richard A.
Publié 2012

Mixture-Based Heterocyclic Combinatorial Positional Scanning Libraries: Discovery of Bicyclic Guanidines Having Potent Antifungal Activities against Candida albicans and Cryptococ...

par Blondelle, Sylvie E., Crooks, Ema, Ostresh, John M., Houghten, Richard A.
Publié 1999

The role of imidazole in peptide cyclization by transesterification: parallels to the catalytic triads of serine proteases

par Byler, Kendall G., Li, Yangmei, Houghten, Richard A., Martinez-Mayorga, Karina
Publié 2013

Shifting from the single- to the multitarget paradigm in drug discovery

par Medina-Franco, José L., Giulianotti, Marc A., Welmaker, Gregory S., Houghten, Richard A.
Publié 2013

Palladium-Catalyzed C-H Functionalization Using Guanidine as a Directing Group: Ortho Arylation and Olefination of Arylguanidines

par Shao, Jiaan, Chen, Wenteng, Giulianotti, Marc A., Houghten, Richard A., Yu, Yongping
Publié 2012

Libraries from Libraries: A Series of Sulfonamide Linked Heterocycles Derived from the Same Scaffold

par Debevec, Ginamarie, Chen, Wenteng, Yu, Yongping, Houghten, Richard A., Giulianotti, Marc A.
Publié 2013

Parallel Synthesis of 1,6-Disubstituted-1,2,4-Triazin-3-Ones on Solid-Phase

par Hu, Miao, Huang, Wei, Giulianotti, Marc A., Houghten, Richard A., Yu, Yongping
Publié 2013

Conditional Probabilistic Analysis for Prediction of the Activity Landscape and Relative Compound Activities

par Santos, Radleigh G., Giulianotti, Marc A., Houghten, Richard A., Medina-Franco, José L.
Publié 2013

An N-methyl-d-aspartate receptor channel blocker with neuroprotective activity

par Tai, Kwok-Keung, Blondelle, Sylvie E., Ostresh, John M., Houghten, Richard A., Montal, Mauricio
Publié 2001

Chemoinformatic Analysis of Combinatorial Libraries, Drugs, Natural Products and Molecular Libraries Small Molecule Repository

par Singh, Narender, Guha, Rajarshi, Giulianotti, Marc, Pinilla, Clemencia, Houghten, Richard, Medina-Franco, Jose L.
Publié 2009

Synthesis of Cyclic Peptides through Direct Aminolysis of Peptide Thioesters Catalyzed by Imidazole in Aqueous Organic Solutions

par Li, Yangmei, Yongye, Austin, Giulianotti, Marc, Martinez-Mayorga, Karina, Yu, Yongping, Houghten, Richard A.
Publié 2009

Activity of ADAM17 (a Disintegrin and Metalloprotease 17) Is Regulated by Its Noncatalytic Domains and Secondary Structure of its Substrates

par Stawikowska, Roma, Cudic, Mare, Giulianotti, Marc, Houghten, Richard A., Fields, Gregg B., Minond, Dmitriy
Publié 2013

Glycosylation of A Disintegrin And Metalloprotease 17 (ADAM17) Affects its Activity and Inhibition

par Chavaroche, Anais, Cudic, Mare, Giulianotti, Marc, Houghten, Richard A., Fields, Gregg B., Minond, Dmitriy
Publié dans Anal Biochem (2013)