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An N-methyl-d-aspartate receptor channel blocker with neuroprotective activity

Excitotoxicity, resulting from sustained activation of glutamate receptors of the N-methyl-d-aspartate (NMDA) subtype, is considered to play a causative role in the etiology of ischemic stroke and several neurodegenerative diseases. The NMDA receptor is therefore a target for the development of neur...

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Autori principali: Tai, Kwok-Keung, Blondelle, Sylvie E., Ostresh, John M., Houghten, Richard A., Montal, Mauricio
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC30685/
https://ncbi.nlm.nih.gov/pubmed/11248110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061449498
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