An N-methyl-d-aspartate receptor channel blocker with neuroprotective activity

Excitotoxicity, resulting from sustained activation of glutamate receptors of the N-methyl-d-aspartate (NMDA) subtype, is considered to play a causative role in the etiology of ischemic stroke and several neurodegenerative diseases. The NMDA receptor is therefore a target for the development of neur...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Tai, Kwok-Keung, Blondelle, Sylvie E., Ostresh, John M., Houghten, Richard A., Montal, Mauricio
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2001
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30685/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11248110/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.061449498
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