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Shifting from the single- to the multitarget paradigm in drug discovery
Increasing evidence that several drug compounds exert their effects through interactions with multiple targets is boosting the development of research fields that challenge the data reductionism approach. In this article, we review and discuss the concepts of drug repurposing, polypharmacology, chem...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3642214/ https://ncbi.nlm.nih.gov/pubmed/23340113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2013.01.008 |
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