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Ligandomics: a paradigm shift in biological drug discovery
As productivity of pharmaceutical research and development (R&D) for small-molecule drugs declines, the trend in drug discovery strategies is shifting towards biologics, which predominantly target secreted or cell surface proteins. Receptors and ligands are the most-valuable drug targets. In con...
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| Опубликовано в: : | Drug Discov Today |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5849512/ https://ncbi.nlm.nih.gov/pubmed/29326083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2018.01.013 |
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